Reduction of glycosyl β-amino esters (6-14 and 25-30) with lithium aluminium hydride resulted in glycosyl amino alcohols (15-23 and 31-36) in good yields. However, reductive amination of glycosyl aldehydes (1, 2 and 3) ...

A series of azatricyclodiones and octahydro-benzo[f]isoindoles have been synthesized by (4+2) Diels-Alder cycloaddition of maleimides with furfuryl amine. Reaction of azatricyclodiones with isocyanates led to respective ...

An efficient synthesis of glycosyl dihydropyrimidinones using a three-component reaction of a β-keto ester, glycosyl aldehyde, urea (or thiourea) in the presence of tetrabutylammonium hydrogensulphate and diethylene glycol ...

Filariasis, caused by spirunid nematodes, is one of the most prevalent diseases of tropical and subtropical countries and encompasses a number of different pathological conditions. The most common type of filariasis is a ...

5,6-O- isopropylidene-2,3- di-O- methyl ascorbic acid (2), obtained by reaction of acetone with ascorbic acid (1) followed by methylation with methyl iodide, on DBU catalysed elimination of acetone moiety led to the formation ...

Reaction of 5,6-O-isopropylidene-2,3-bis-O-alkyl ascorbic acid with different amines in the presence of DBU at ambient temperature resulted in the formation of 3,4-bis-O-alkyl-1-alkyl-5-(2-hydroxy ethyl)-5-hydroxy-1,5-d ...

Reductive amination is one of the most useful and versatile methods for the preparation of’ amines in biological and chemical systems. The present review focuses on the development of catalytic reductive amination from ...

D-Glucosamine, one of the important sugars of natural origin catalyzes direct aldol reaction of different aromatic aldehydes with acyclic or cyclic ketones. Diastereo- and enantioselection varies with the substituent on ...

Direct asymmetric aldol reaction of acetone with aromatic aldehydes using hitherto unprecedented glycosyl acyclic amino acid as a new organocatalyst with high enantioselectivity and good yields is reported.

DNA ligases (EC.6.5.1.1) are key enzymes that catalyze the formation of phosphodiester bonds at single stranded or double stranded breaks between adjacent 5’phosphoryl and 3’ hydroxyl groups of DNA. These enzymes are ...