A series of 2,4,6-trisubstituted pyrimidines and 1,3,5-triazines have been synthesized and screened for their in vitro and in vivo antileishmanial activity against L. donovani. Among all, 14 compounds have shown promising ...

One of the alkaloids isolated from the roots of Cissampelos pareira Linn. has been identified as cycleanine. Some discrepancies in its nuclear magnetic resonance spectrum reported earlier by Bick et al. [J. chem. Soc., ...

A number of I-pyridyl-4-substituted piperazines have been synthesized and evaluated for their pharmacological action. A number of 1-(3-amino-4-pyridyl)-4-phenylpiperazines have been shown to possess marked anticonvulsant and ...

[1:-Isoleucine,5-isoleucine]-angiotensin II and [3-proline,5-isoleucine]-angiotensin II were synthesized by the solid-phase method using dicyclohexylcarbodiimide as the condensing agent. The formation of the arginyl-proline ...

During synthesis aimed at obtaining 4-beta-chloroethylamino and 4-bis-beta-chloroethylamino pyrimidines, it has been found that treatment of 2-chloro-4-bis-beta-hydroxyethylaminopyrimidine with hydrochloric acid or of ...

The incorporation of (+ or -)-,(+)-,and (-)-coclaurine into crotonosine in Croton linearis Jacq has been investigated and the specific utilization of the (+)-isomer demonstrated.The isomeric (+ or -)-isococlaurine is not ...

From the roots of Berberis asiatica Roxb., berberine, palmitine, jatrorrhizine, columbamine, tetrahydropalmitine, berbamine, oxyberberine and oxyacanthine have been isolated. Berberine and palmitine occur as chlorides.