Abstract:
The incorporation of (+ or -)-,(+)-,and (-)-coclaurine into crotonosine in Croton linearis Jacq has been investigated and the specific utilization of the (+)-isomer demonstrated.The isomeric (+ or -)-isococlaurine is not a precursor of crotonosine although (+ or -)-norcoclaurine is incorporated. The evedence supports the oxidative cyclisation of (+)-coclaurine to a dienone.