OBJECTIVES The genetic and cellular processes involved in aetiopathology of BPH are unknown. Though there is growing evidence of BPH as immune-mediated diseases distinct from prostate cancer, still cytokine gene polymorphisms ...

Breast cancer is the most common cancer and the leading cause of cancer death in women. Although tamoxifen therapy is successful for some patients, it does not provide adequate benefit for those who have estrogen receptor ...

In the course of our studies on the isolation of bioactive compounds from the roots of Coleus forskohlii, a traditional herb in India, rare 13-epi-sclareol has been isolated, and its structure determined by extensive 2D ...

Estrogen deficiency leads to an upregulation of TNF-a producing T cells and B-lymphopoesis which augments osteoclastogenesis. Estrogen deficiency also increases the population of premature senescent CD4+CD28null T cells ...

Context: Asparagus adscendens Roxb (Liliaceae) has a promising role in modulation of various disorders such as leucorrhea, diarrhea, dysentery, diabetes, senile pruritus, asthma, fatigue antifilarial, antifungal, spermatorrhea, ...

Estradiol dipropionate exerts an inhibitory acton on the development of Trypanosoma equiperdum in rats and mice. thereby prolonging the survival time of the infected animals. It is suggested that the hormone influences the ...

Thiourea treatment causes structural and functional changes in the testis of young rats. There is some disorganization of the seminiferous epithelium and many of the Leydig cells also undergo atrophy. The total cholesterol ...

Adrenalectomy causes an increase in parasitemia and an acceleration of mortality rate in rats. This is probably due to the Iowertng of host resistance or to further increase in hypoglycemia produced by trypanosome ...

Activated T cell has a key role in the interaction between bone and immune system. T cells produce pro-inflammatory cytokines including, RANKL, TNF-α and IL-17, all of which augment osteoclastogenesis. RANKL and TNF- are ...