The intraduodenal route for administering drugs in experimental animals in acute pharmacodynamic experiments has been tried. Drugs which are absorbed from the duodenum give a prompt response. When crude extracts of the ...

Ribonucleic acid depolynlerizing activity in certain cell-free preparations and resting cell suspensions of Vibrio cholerae has been Investigated.Though the intact cells are entirely inactive, crude extracts obtained by ...

The in vivo and in vitro amoebicidal activities of emetine, conessine, quinine,quinidine and chloro, dihydro and hexahydro derivatives of desoxy quinine and quinidine have been determined employing weanling albino rat as ...

The development of a vaccine against visceral leishmaniasis (VL) conferring long-lasting immunity remains a challenge. Identification and proteomic characterization of parasite proteins led to the detection of p45, a member ...

The hierarchical virtual screening (VS) study, consisting of pharmacophore modelling, docking, and VS of the generated focussed virtual library, has been carried out to identify novel high-affinity and selective β3-AR ...

Aims: The aim of the present study is to investigate the status of proinflammatory cytokine in the brain of intracerebroventricular (ICV) okadaic acid (OKA) induced memory impaired rat. Main methods: OKA (200ng) ...

Infectious disease caused by parasites continues to take a massive toll on human health in the poor regions of the world. Filling the antiinfective drug discovery pipeline has never been as challenging as it is now. The ...

The macroscopic and microscopic characters of the root and leaf of Coccinia indica, which is reputed to be effective in the treatment of diabetes, are described.

The synthesis of some 4-oxypyrimido-(4,5-d)- pyrimidines and 2:4-dioxypyrimido-(4,5-d)- pyrimidines is reported. The synthesis is effected by the cyclization of the respective 2- substituted -4-aminopyrimidine -5-carboxamides ...