Endocrinology: Recent submissions

Now showing items 41-55 of 55

A Study on Corticotrophin (ACTH) estrogen Interactions on the Genital Organs of Young Female Rats

Kar, A B (1955)

Corticotrophin exerts a stimulating effect on the genital organs of young female rats probably through an acceleration of pituitary gonadotrophin output. Estradiol dipropionate suppresses ovarian function through an ...
The Effects of Progesterone, Serum Gonadotrophin & Testosterone Propionate on Histology & Total Ascorbic Acid Content of the Adrenal of the Rat

Kar, A B; Roy, A C; Karkun, J N (1953)

Intramuscular injections of progesterone, serum gonadotrophtn and testosterone propionate cause.atrophic changes and decline in ascorbic acid content of the rat's adrenal cortex.The severity of cellular atrophy and the ...
The Effect of Estradiol Dipropionate on the Development of Trypanosoma equiperdum in Rats & Mice

Chak, I M; Kar, A B (1954)

Estradiol dipropionate exerts an inhibitory acton on the development of Trypanosoma equiperdum in rats and mice. thereby prolonging the survival time of the infected animals. It is suggested that the hormone influences the ...
Effect of Experimental Tuberculosis on the Distribution of Alkaline Phosphatase in the Adrenal Cortex of the Guinea Pig

Kar, A B (1954)
Role of Interleukin-10 in Breast Cancer

Hamidullah; Changkija, Bendangla; Konwar, Rituraj (2012)

Cytokines are low molecular weight regulatory proteins or glycoprotein that modulates the intensity and duration of immune response by stimulating or inhibiting the activation, proliferation and/or differentiation of target ...
ErbB family receptor inhibitors as therapeutic agents in breast cancer: Current status and future clinical perspective

Saxena, Ruchi; Dwivedi, Anila (2012)

Breast cancer is the most common cancer diagnosed in women and the second most common cause of female cancer related deaths with more than one million new cases diagnosed per year throughout the world. With the recent ...
Methoxylated isoflavones, cajanin and isoformononetin, have non-estrogenic bone forming effect via differential mitogen activated protein kinase (MAPK) signaling

Bhargavan, Biju; Gautam, A K; Singh, Divya; Kumar, Amit; Chaurasia, Sumit; Tyagi, A M; Yadav, D K; Mishra, J S; Singh, Amar B; Sanyal, Sabyasachi; Goel, Atul; Maurya, Rakesh; Chattopadhyay, Naibedya (2009)

Following a lead obtained from stem-bark extract of Butea monosperma, two structurally related methoxyisoflavones; cajanin and isoformononetin were studied for their effects in osteoblasts. Cajanin had strong mitogenic as ...
Role of ethnic variations in TNF-alfa and TNF-bita polymorphisms and risk of breast cancer in India

Singh, P; Bid, H K; Francis, Amirtharaj; Kumar, Sandeep; Singh, Rajender; Ramalingam, K; Thangaraj, Kumarasamy; Konwar, Rituraj (2010)

TNF-alfa and -bita are multi-functional pro-inflammatory cytokines known to play important roles in both tumor progression and destruction based on their concentrations. Growth factors and various stimuli such as cytokines ...
Glutathione S-transferase (GST) Gene Variants and risk of BPH (Benign Prostatic Hyperplasia): A report in north Indian population

Konwar, Rituraj; Manchanda, P K; Chaudhary, Preeti; Nayak, V L; Singh, Vishwajeet; Bid, H K (2010)

GST is over expressed in BPH patients. Nature of association of GST polymorphism with susceptibility of BPH as a disease different from prostate is limited. The objectives of this study was to determine relationship between ...
Role of phytochemicals in the prevention of menopausal bone loss: evidence from in vitro and in vivo, human interventional and pharmacokinetic studies

Sharan, Kunal; Siddiqui, J A; Swarnkar, Gaurav; Maurya, Rakesh; Chattopadhyay, Naibedya (2009)

Substantial body of data generated from cultured bone cells and rat models of osteoporosis support a significant bone-conserving effect of phytochemicals. Flavonoids including isoflavones, stilbenes and lignans with variable ...
Breast Cancer Risk Associated with Polymorphisms of IL-1RN and IL-4 Gene in Indian Women

Konwar, Rituraj; Chaudhary, Preeti; Kumar, Sandeep; Mishra, Deepti; Chattopadhyay, Naibedya; Bid, H K (2009)

BACKGROUND: Interleukins and cytokines are important regulator of the aetio-pathogenesis of majority of cancers. Mechanistic role of IL-1RN and IL-4 particularly in breast carcinogenesis is well documented. However, the ...
Cell growth inhibitory action of an unusual labdane diterpene, 13-epi-sclareol in breast and uterine cancers in vitro

Sashidhara, K V; Rosaiaha, J N; Kumar, Abdhesh; Bid, H K; Konwar, Rituraj; Chattopadhyay, Naibedya (2007)

In the course of our studies on the isolation of bioactive compounds from the roots of Coleus forskohlii, a traditional herb in India, rare 13-epi-sclareol has been isolated, and its structure determined by extensive 2D ...
Association of IL-4 and IL-1RN (receptor antagonist) gene variants and the risk of type 2 diabetes mellitus: a study in the north Indian population

Bid, H K; Rituraj, Konwar; Agrawal, C G; Banerjee, Monisha (2008)

Background: Inflammation is a key event closely associated with the pathophysiology of type 2 diabetes mellitus (T2DM). Association of genetic polymorphisms of inflammatory cytokines with T2DM is largely unknown. Our ...
Genetic Polymorphism and Pathogenesis of Benign Prostatic Hyperplasia (BPH)

Konwar, Rituraj; Chattopadhyay, Naibedya; Bid, H K (2008)

There is apparent uncertainty in etiology and pathogenesis of Benign Prostatic Hyperplasia. Though several hypothesis put forwarded, like other multifactorial complex diseases, BPH still lacks an integrated model of ...
Association of IL-4 and IL-1 Receptor Antagonist (IL-1Ra) Gene Polymorphisms and the Risk of Benign Prostatic Hyperplasia (BPH)

Konwar, Rituraj; Gara, Rishi; Singh, Manmohan; Singh, Vishwajeet; Chattopadhyay, Naibedya; Bid, H K (2008)

OBJECTIVES The genetic and cellular processes involved in aetiopathology of BPH are unknown. Though there is growing evidence of BPH as immune-mediated diseases distinct from prostate cancer, still cytokine gene polymorphisms ...

Now showing items 41-55 of 55

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