Pharmaceutics: Recent submissions

Now showing items 41-48 of 48

Untitled

Unknown author (2011-08-18)

Gene silencing by RNA interference has rapidly growing area of therapeutic for managing diseases. Besides research advances in this direction, the poor cellular uptake of synthetic small interfering RNAs is a major impediment ...
SiRNA Delivery Challenges and Role of carrier Systems

Shegokar, R; Al Shaal, L; Mishra, P R (2011)

Gene silencing by RNA interference has rapidly growing area of therapeutic for managing diseases. Besides research advances in this direction, the poor cellular uptake of synthetic small interfering RNAs is a major impediment ...
Inhalable Microparticles Containing Isoniazid and Rifabutin Target Macrophages and “Stimulate the Phagocyte” to Achieve High Efficacy

Yadav, A B; Sharma, Rolee; Muttil, Pavan; Singh, A K; Verma, R K; Mohan, Mradul; Patel, S K; Misra, Amit (2009)

Macrophage responses to infection with Mycobacterium tuberculosis (MTB) and treatment with soluble isoniazid (INH) plus rifabutin (RFB) versus microparticles containing equivalent amounts of drugs were compared. It was ...
Inhalable Microparticles Containing Isoniazid and Rifabutin Target Macrophages and “Stimulate the Phagocyte” to Achieve High Efficacy

Yadav, A B; Sharma, Rolee; Muttil, Pavan; Singh, A K; Verma, R K; Mohan, Mradul; Patel, S K; Misra, Amit (2009)

Macrophage responses to infection with Mycobacterium tuberculosis (MTB) and treatment with soluble isoniazid (INH) plus rifabutin (RFB) versus microparticles containing equivalent amounts of drugs were compared. It was ...
A Hand-Held Apparatus for “Nose-Only” Exposure of Mice to Inhalable Microparticles as a Dry Powder Inhalation Targeting Lung and Airway Macrophages

Kaur, Jatinder; Muttil, Pavan; Kumar, Kaushlendra; Verma, Rahul; Yadav, A B; Sharma, Rolee; Misra, Amit (2008)

A hand-held apparatus designed for the purpose of administering dry powder inhalations to rodents by “Nose-only” exposure was standardized. An aerosol of microparticles containing the anti-tuberculosis drugs isoniazid and ...
Inhalable Microparticles Containing Large Payload of Anti-tuberculosis Drugs

Muttil, Pavan; Kaur, Jatinder; Kumar, Kaushlendra; Yadav, A B; Sharmaa, Rolee; Misra, Amit (2007)

Microparticles containing large payloads of two anti-tuberculosis (TB) drugs were prepared and evaluated for suitability as a dry powder inhalation targeting alveolar macrophages. A solution containing 1 part each of ...
Uptake of inhalable microparticles affects defense responses of macrophages infected with Mycobacterium tuberculosis H37Ra.

Sharma, Rolee; Muttil, Pavan; Yadav, A B; Rath, S K; Bajpai, V K; Mani, Uthirappan; Misra, Amit (2007)
Inhalable microparticles containing large payload of antituberculosis

Kaur, Jatinder; Kumar, Kaushlendra; Yadav, A B; Sharma, Rolee; Misra, Amit; (2007)

Microparticles containing large payloads of two anti-tuberculosis (TB) drugs were prepared and evaluated for suitability as a dry powder inhalation targeting alveolar macrophages. A solution containing one part each of ...

Now showing items 41-48 of 48

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