A novel class of 2,3,4-triarylbenzopyrans has been synthesized and were evaluated for their selective estrogen receptor rmodulation and anti-proliferative activities. 10a and 11c exhibited 73.91 and 69.24 % inhibition as ...

Frequency of malaria and its resistance to chemotherapeutic options are emerging rapidly. To counter this problem, a series of 4–aminoquinolines having oxalamide and triazine functionalities in the side chain were synthesized ...

The histamine H4 receptor binding affinity of 2-(4-Methylpiperazin-1-yl)quinoxaline derivatives have been quantitatively analyzed in terms of Dragon descriptors. The derived QSAR models have provided rationales to explain ...

A new stereoselective synthesis of 2-susbstituted amino-5,6-dihydro 4H-1,3-thiazines using primary allylamines obtained from the Morita-Baylis-Hillman (MBH) acetates is described. The primary allylamines react with aryl ...

Synthesis of a variety of annulated triazoles and tetrazoles from differently substituted allyl azides, afforded from the Baylis-Hillman adduct of acrylates, using intramolecular cycloaddition approach is described.

Activity guided fractionation of the ethanolic extract of the leaves of the P. longifolia var. pendula led to the identification of quercetin 1, quercetin-3-O-ß-glucopyranoside 2, kaempferol-3-O-α-rhamnopyranosyl-(1→6)- ...

A small library of novel benzocoumarin derivatives based on naturally occurring neo-tanshinlactone scaffold was constructed and their antiproliferative activities against breast cancer cells MCF-7 & MDA-MB-231 were evaluated. ...

An easy, efficient and concise approach to tetrahydrofluorene [6, 5, 6] ABC tricyclic core embedded new polycycles have been achieved under relatively mild and catalytic Nazarov type electrocyclization using 2 mol% of ...

The objective of this study was to determine the in vitro osteogenic activities of selected medicinal plants used traditionally in India. The compounds isolated from three plants viz. Allophylus serratus, Cissus quadrangularis ...

Phytochemical investigation of Annona squamosa twigs, resulted in isolation and identification of twelve known (1-12) compounds among them one 1-(4-β-D-glucopyranosyloxyphenyl)-2-(β-D-glucopyranosyloxy)-ethane (11) is ...