SiRNA Delivery Challenges and Role of carrier Systems

Shegokar, R; Al Shaal, L; Mishra, P R

dc.contributor.author	Shegokar, R
dc.contributor.author	Al Shaal, L
dc.contributor.author	Mishra, P R
dc.date.accessioned	2011-06-03T04:26:11Z
dc.date.available	2011-06-03T04:26:11Z
dc.date.issued	2011
dc.identifier.citation	Pharmazie, 66(5), 313-318	en
dc.identifier.uri	http://hdl.handle.net/123456789/679
dc.description.abstract	Gene silencing by RNA interference has rapidly growing area of therapeutic for managing diseases. Besides research advances in this direction, the poor cellular uptake of synthetic small interfering RNAs is a major impediment for their clinical applications. Polymer and lipid-based systems are attractive carrier systems for delivery of siRNA and provides option of desirable engineering of carriers particles. In this review, a detailed discussion is done about RNAi delivery systems and recent advances in the field.	en
dc.format.extent	450550 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI COMMUNICATION NO.8005	en
dc.subject	SiRNA	en
dc.subject	delivery systems	en
dc.subject	lipid nanoparticles	en
dc.subject	polymeric carriers	en
dc.subject	targeting	en
dc.title	SiRNA Delivery Challenges and Role of carrier Systems	en
dc.type	Article	en