Liposome-mediated drug delivery systems along with other newer approaches of drug targeting have revolutionized the measures of controlling parasitic infections, including, malaria, leishmania, fungal infections, besides ...

To understand the role of host cell cytoskeleton in regulating the assembly and budding of the externally enveloped viruses, we have studied the interactions between the cytoskeleton and viral proteins in the influenza A ...

Tuftsin is a tetrapeptide (Thr-Lys-Pro-Arg)that specifically binds monocytes, macrophages, and polymorphonuclear leukocytes and potentiates their natural killer activity against tumors and pathogens. The antimicrobial ...

The sn-glycerol moiety in 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) was replaced by the rac-1,2,4-butanetriol residue, and the aqueous dispersions of the resulting DPPC analogs, viz. 1,2-dihexadecanoyloxy-rac-bu ...

Hydrogel nanoparticles of cross-linked polyvinylpyrrolidone (PVP-NP) (35-50 nm in diameter) containing fluoresceinated dextran (FITC-Dx) were encapsulated in reconstituted Sendai viral envelopes containing only the fusion ...

To study the occurrence and subcellular distribution of actin in trypanosomatid parasites, we have cloned and overexpressed Leishmania donovani actin gene in bacteria, purified the protein, and employed the affinity purified ...

The ATP binding cassette (ABC) transporters are a large family of proteins responsible for the translocation of a variety of compounds across the membranes of both prokaryotes and eukaryotes. The inter-protein and intra-protein ...

Infectivity of Leishmania promastigotes has been shown to be growth cycle-dependent and restricted to the stationary phase. By using annexin V-FITC binding and procoagulant activity measurement assays, we show here that ...

To understand the role of the ester mioety of the sn-1 acyl chain in phospolipase A2- glycerophospholipid interaction, we introduced an additional methylene residue between the glycerol CI and C2 carbon atoms of ...

The effect of protease inhibitors obtained from the culture filtrates of actinomycetes(pepstatin, chymostatin, leupeptin, phosphoramidon and elastatinal)on the in vitro inbasion of erythrocytes from rhesus and assanese ...