Interactions can be broadly classified as covalent and noncovalent. Noncovalent interactions are those interactions which does not involve sharing of electrons. Noncovalent interactions form a very wide domain of weak ...

Leishmaniasis is a zoonotic protozoan disease caused by Leishmania. The disease is widely distributed, affecting approximately 12 million people worldwide; causing a wide spectrum of diseases. Leishmaniasis affects the ...

Okadaic acid (OKA) is a selective inhibitor of the serine/threonine phosphatases 1 (PP1) and 2A (PP2A) and considered as a main culprit for memory impairment in the aged population using sea foods dinoflagellates ...

Diseases produced by protozoan parasites are one of the main cause of morbidity and mortality around the world, affecting millions of people. Leishmaniasis is a disease complex caused by the species of haemoflagellate protozoan ...

Keeping in mind the ultimate goal as to be able to design and synthesize better ligands as potent drug candidates, medicinal chemist needs new chemical entities (NCEs) with the incorporation of knowledge from other advance ...

Nuclear receptors are a large family of structurally related ligands-inducible transcription factor, including steroid receptor (SRs), thyroid/retinoid receptors (TR, RARs, RXRs), vitamin D receptor (VDR), LXR, PPARS and ...

Heterocycles constitute the largest diversity of organic molecules of chemical, biomedical, and industrial significance. They widely exist in numerous natural products, such as vitamins, hormones, antibiotics, alkaloids, ...

The development in genetic engineering has led to a proliferation of large quantities and varieties of proteins, which are highly pure and free from biological contaminants. In spite of their potency and specificity ...

Immune system is a complex network of interdependent cells that collectively protect the body from bacterial, parasitic, fungal, viral infections and from the growth of tumor cells. Sometimes the immune system fails to ...

The human race & natural products are coexisting since ages and their co-evolution has led to the possibility of finding new drugs for various diseases from this perpetual source-the nature. It must be emphasized that any ...