The relationship between the benzylisoquinoline alkaloid coclaurine and the aporphine alkaloid roemerine in papaver dubium L.has been studied. Various congeners of coclaurine have also been utilised in the investigation ...

The reported ambiguity in the physical characteristics of beta-methyl aspartate hydrochloride has been found to be due to the presence of formed from the former on storage.

Ozonolysis of tritiated Salutaridinols-I and-II has afforded glyceric acids whose absolute confiurations have been determined by the isotope dilution method.In this way the stereochemistry of salutaridinol-I, the Precursor ...

The apprataus, designed for solid phase peptide synthesis, consist of a round-bottom flask,rocked on a wrist-shaker,and fitted with a special dropping funnel and a fritted filter disc embedded with in the flask.The dropping ...

The regioselective decarboxylation during the saponification of the nitroalkanoates synthesized from the Baylis-Hillman acetates of acrylates to stereoselectively afford homoallyl nitroalkane is described. In contrast the ...

First report of stereoselective synthesis of substituted allyl isonitriles from the primary allyl amines generated from the Baylis-Hillman adduct and its utilization in a robust IMCR to afford substituted imidazo[1,2-a]pyridine ...

Syntheses and in vitro antimalarial evaluation of 42 new thioureido quinazolines have been carried out. Several analogs showed promising antimalarial effect in the in vitro investigation against chloroquine-sensitive 3D7 ...

A total of 80 new 2-methyl-6-ureido-4-quinolinamides were synthesized and evaluated for their anitmalarial activity. Several analogs elicited the antimalarial effect at MIC of 0.25 mg/mL against the chlooquine-sensitive ...