Stereoselective synthesis of homoallyl nitroalkane derivatives via base-promoted regioselective decarboxylation in Baylis-Hillman derivatives

Abstract

The regioselective decarboxylation during the saponification of the nitroalkanoates synthesized from the Baylis-Hillman acetates of acrylates to stereoselectively afford homoallyl nitroalkane is described. In contrast the similar nitroalkanoates derived from the Baylis-Hillman acetates of acrylonitrile gave bis allyl nitroalkanes.