Frequency of malaria and its resistance to chemotherapeutic options are emerging rapidly. To counter this problem, a series of 4–aminoquinolines having oxalamide and triazine functionalities in the side chain were synthesized ...

A series of 2,4,6-trisubstituted pyrimidines and 1,3,5-triazines have been synthesized and screened for their in vitro and in vivo antileishmanial activity against L. donovani. Among all, 14 compounds have shown promising ...

One of the alkaloids isolated from the roots of Cissampelos pareira Linn. has been identified as cycleanine. Some discrepancies in its nuclear magnetic resonance spectrum reported earlier by Bick et al. [J. chem. Soc., ...

A number of I-pyridyl-4-substituted piperazines have been synthesized and evaluated for their pharmacological action. A number of 1-(3-amino-4-pyridyl)-4-phenylpiperazines have been shown to possess marked anticonvulsant and ...

5-Styryl-4, 5-cis-1, 3-oxazole-2-one-4-carboxylic acid (CDRI-85/92) is a new proton pump inhibitor presently in advanced stage of preclinical trials as antiulcer pharmacophore. Since proton pump inhibitors are prodrugs ...

[1:-Isoleucine,5-isoleucine]-angiotensin II and [3-proline,5-isoleucine]-angiotensin II were synthesized by the solid-phase method using dicyclohexylcarbodiimide as the condensing agent. The formation of the arginyl-proline ...

Sodium and liquid ammonia reduction of hayatinin ethyl ether affords a non-phenolic component, identified as dl-4'-O-methyl-7-0-ethyl-N-methylcoclaurine, and a phenolic component identified as dl-N-methylcoclaurine. The ...

1-Isoleucine,5-isoleucine]-angiotensin II and [3-proline,5-isoleucine]-angiotensin II were synthesized by the solid-phase method using dicyclohexylcarbodiimide as the condensing agent. The formation of the arginyl-proline ...