Abstract:
Parenteral administration of DL,α tocopherol acetate during the development of experimental atherosclerosis produced progressive hypercholesterolaemia
and β lipoproteinaemia with a marked rise of C/P ratio and β cholesterol. In the
untreated animals fed with cholesterol in olive oil, peak of hypercholesterolaemia
was noted at six weeks which was maintained up to twelve weeks. Feeding of
olive oil alone did not give rise to an increase of serum cholesterol level but
produced relative increase of serum β- lipoproteins