Synthesis of 2-amino-3,4-dihydroquinazolines and imidazo[2,1-b]quinazoline-2-ones

Mishra, Amita; Batra, Sanjay

dc.contributor.author	Mishra, Amita
dc.contributor.author	Batra, Sanjay
dc.date.accessioned	2010-03-02T09:08:29Z
dc.date.available	2010-03-02T09:08:29Z
dc.date.issued	2009
dc.identifier.citation	Synthesis 2009, no. 18, 3077-88	en
dc.identifier.uri	http://hdl.handle.net/123456789/521
dc.description.abstract	A facile method for the synthesis of 2-amino-3,4-dihydroquinazolines from the Baylis-Hillman derivatives has been disclosed. The protocol involves the sequential SN2-reaction of a primary amine on the Baylis-Hillman acetate of 2-nitrobenzaldehyde, CNBr-mediated nitrile addition and Fe-AcOH-promoted reductive cyclization. The approach has been extended for constructing imidazo[2,1-b]quinazoline-2-ones and imi-dazo[2,1-b]qinazolines in one pot.	en
dc.format.extent	274105 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication Number 7780	en
dc.subject	Quinazoline	en
dc.subject	Anagrelide	en
dc.subject	Baylis-Hillman	en
dc.subject	imidazo[2,1-b]quinazoline	en
dc.subject	allyl amine	en
dc.title	Synthesis of 2-amino-3,4-dihydroquinazolines and imidazo[2,1-b]quinazoline-2-ones	en
dc.type	Article	en