A facile route to the synthesis of pyrimido[2,1-b]quinazoline core from the primary allyl amines afforded from Baylis-Hillman adducts

Nag, Somnath; Mishra, Amita; Batra, Sanjay

dc.contributor.author	Nag, Somnath
dc.contributor.author	Mishra, Amita
dc.contributor.author	Batra, Sanjay
dc.date.accessioned	2009-09-15T09:31:55Z
dc.date.available	2009-09-15T09:31:55Z
dc.date.issued	2008
dc.identifier.citation	Tetrahedron 64 (2008) 10162–10171	en
dc.identifier.uri	http://hdl.handle.net/123456789/513
dc.description.abstract	A highly simplified approach for the generation of substituted pyrimido[2,1-b]quinazoline core from the primary allyl amines afforded from the Baylis-Hillman adducts is described. Sequential reductive alkylation of the primary allyl amine with 2-nitrobenzaldehyde, reduction of the aromatic nitro group with In, CNBr-promoted intramolecular cyclization followed by NaOMe-mediated another intramolecular cyclization furnish the title compounds.	en
dc.format.extent	259422 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication No 7563	en
dc.subject	Baylis-Hillman	en
dc.subject	Allyl amine	en
dc.subject	BrCN, pyrimido[2,1-b]quinazoline	en
dc.subject	In	en
dc.subject	intramolecular cyclization	en
dc.title	A facile route to the synthesis of pyrimido[2,1-b]quinazoline core from the primary allyl amines afforded from Baylis-Hillman adducts	en
dc.type	Article	en