Synthesis of Galactopyranosyl Amino Alcohols as a new class of Antitubercular and Antifungal Agents

Tewari, Neetu; Tiwari, V K; Tripathi, R P; Chaturvedi, Vinita; Srivastava, A; Srivastava, R; Shukla, P K; Chaturvedi, A K; Gaikwad, A; Sinha, S; Srivastava, B S

dc.contributor.author	Tewari, Neetu
dc.contributor.author	Tiwari, V K
dc.contributor.author	Tripathi, R P
dc.contributor.author	Chaturvedi, Vinita
dc.contributor.author	Srivastava, A
dc.contributor.author	Srivastava, R
dc.contributor.author	Shukla, P K
dc.contributor.author	Chaturvedi, A K
dc.contributor.author	Gaikwad, A
dc.contributor.author	Sinha, S
dc.contributor.author	Srivastava, B S
dc.date.accessioned	2009-02-10T19:22:02Z
dc.date.available	2009-02-10T19:22:02Z
dc.date.issued	2004
dc.identifier.citation	Bio. Med. Chem.Lett.12,329 (2004)	en
dc.identifier.uri	http://hdl.handle.net/123456789/312
dc.description.abstract	The galactopyranosyl amino alcohols (3-16) were synthesized by regioselective oxirane ring opening of compound 2 with variety of amines and screened for antitubercular and antifungal activities. One of the compounds (16) showed potent activity against M. tuberculosis H37 Rv in vitro and also displayed activity in MDR TB. The compound (16) was found to be superior to ethambutol clinically used anti TB drug in in vitro screen.	en
dc.format.extent	156349 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI communication No 6442	en
dc.title	Synthesis of Galactopyranosyl Amino Alcohols as a new class of Antitubercular and Antifungal Agents	en
dc.type	Article	en