Liposomes mediated drug delivery in infectious diseases

Abstract

Liposome-mediated drug delivery systems along with other newer approaches of drug targeting have revolutionized the measures of controlling parasitic infections, including, malaria, leishmania, fungal infections, besides providing a new approach to control several bacterial infections, including Mycobacterial, Salmonella, Pseudomonas, etc. some of which have acquired resistance. These approaches provide definite reduction in drug toxicity, specially in leishmaniasis and control of candidiasis and other pathogenic fungi. Liposomal drugs, like amphotericin B, would have extensive use in the management of fungal diseases. Liposome mediated drug delivery has an exceptional advantage of biocompatibility, biodegradability, non-immunogenicity and can be used in clinical cases without any side effects.