An efficient combinatorial synthesis of allocolchicine analogs via a triple cascade reaction and inhibition of insulin aggregation

Bhowmik, Subhendu; Khanna, Shruti; Srivastava, Kumkum; Hasanain, Mohammad; Sarkar, Jayanta; Verma, Sandeep; Batra, Sanjay

dc.contributor.author	Bhowmik, Subhendu
dc.contributor.author	Khanna, Shruti
dc.contributor.author	Srivastava, Kumkum
dc.contributor.author	Hasanain, Mohammad
dc.contributor.author	Sarkar, Jayanta
dc.contributor.author	Verma, Sandeep
dc.contributor.author	Batra, Sanjay
dc.date.accessioned	2014-06-24T10:56:16Z
dc.date.available	2014-06-24T10:56:16Z
dc.date.issued	2013
dc.identifier.citation	ChemMedChem, 2013, 8, (11), 1767–1772	en
dc.identifier.uri	http://hdl.handle.net/123456789/1296
dc.description.abstract	Controlled Cascade. A divergent, diastereoselective and efficient synthesis of allocolchicinoids from allylamides prepared from Morita-Baylis-Hillman adducts, via a cascade Suzuki-Michael-Carbocyclization sequence is described. The utility of the compounds as possible inhibitors of insulin aggregation is also presented	en
dc.format.extent	788403 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CSIR-CDRI Communication. No. 8518	en
dc.subject	Alkaloids	en
dc.subject	Antiaggregation agents	en
dc.subject	Cascade reactions	en
dc.subject	Natural products	en
dc.subject	One-pot syntheses	en
dc.title	An efficient combinatorial synthesis of allocolchicine analogs via a triple cascade reaction and inhibition of insulin aggregation	en
dc.type	Article	en