Protection of mice against Plasmodium berghei infection by a tuftsin derivative

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dc.contributor.author Gupta, C M
dc.contributor.author Puri, Anju
dc.contributor.author Jain, Rakesh K
dc.contributor.author Bali, Anu
dc.contributor.author Anand, Nitya
dc.date.accessioned 2008-03-26T07:38:11Z
dc.date.available 2008-03-26T07:38:11Z
dc.date.issued 1986
dc.identifier.citation FEBS Letters (1986), 205, 351-354 en
dc.identifier.uri http://hdl.handle.net/123456789/127
dc.description.abstract In Plasmodium berghei infections, the mortality rate and parasitacmias were significantly reduced and the mean survival time was considerably enhanced by pretreating the animals with a tuftsin derivative, Thr-Lys- Pro-Arg-NH-(CH2)2-NHCOC15H31. This effect of the modified tuftsin was further increased upon its incorporation in the liposome bilayer. These results indicate that tuftsin and its derivatives may prove useful in enhancing nonspecific host resistance against protozoan infections. en
dc.format.extent 1549211 bytes
dc.format.mimetype application/pdf
dc.language.iso en en
dc.relation.ispartofseries CDRI Communication No. 2929 en
dc.subject Protozoan infection en
dc.subject Immunomodulation en
dc.subject Tuftsin en
dc.subject Liposome en
dc.subject Macrophage en
dc.title Protection of mice against Plasmodium berghei infection by a tuftsin derivative en
dc.type Article en


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