Synthesis of Carbamyl and Ether Analogs of Phosphatldylchollnes

Agarwal, Kirti; Bali, Anu; Gupta, C M

dc.contributor.author	Agarwal, Kirti
dc.contributor.author	Bali, Anu
dc.contributor.author	Gupta, C M
dc.date.accessioned	2008-03-23T07:10:23Z
dc.date.available	2008-03-23T07:10:23Z
dc.date.issued	1984
dc.identifier.citation	Chemistry and Physics of Lipids (1984), 36, 169-177	en
dc.identifier.uri	http://hdl.handle.net/123456789/122
dc.description.abstract	A complete synthesis of I-O-hexadecyl-2-O-N-(heptadec-8-cis-enyl)carbamyl-sn-glycer0-3- phosphocholine. a novel analog of phosphatidylcholine, has been described. Each step is simple to perform and gives the desired products in high yield. Also, some of the intermediates formed during the synthesis have been efficiently utilized to prepare 1-O-hexadecyl-2-O-oleyl-snglycero- 3-phosphocholine, I-O-hexadecyl-2-oleoyl-sll-glycero-3-phosphocholine and 3-O-hexadecyl-2-oleoyl-sn-glycero-l-phosphocholine. These phosphatidy1choline (PC) analogs are useful for studying the possible role of phospholipases in the capture and lysis of liposomes in vivo.	en
dc.format.extent	2248839 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication No. 3539	en
dc.subject	liposome	en
dc.subject	drug delivery	en
dc.subject	plasma lipoprotein	en
dc.subject	phosphatidyl analog	en
dc.subject	phospholipases	en
dc.title	Synthesis of Carbamyl and Ether Analogs of Phosphatldylchollnes	en
dc.type	Article	en