Engineering of indole-based tethered biheterocyclic alkaloid Meridianin into -carboline derived tetracyclic polyheterocycles via amino functionalization/6-endo cationic π-cyclization.

Agarwal, P K; Dathi, M D; Saifuddin, Mohammad; Kundu, Bijoy

dc.contributor.author	Agarwal, P K
dc.contributor.author	Dathi, M D
dc.contributor.author	Saifuddin, Mohammad
dc.contributor.author	Kundu, Bijoy
dc.date.accessioned	2013-07-22T09:27:57Z
dc.date.available	2013-07-22T09:27:57Z
dc.date.issued	2012
dc.identifier.citation	Beilstein journal of organic chemistry,2012, 8,1901-1908	en
dc.identifier.uri	http://hdl.handle.net/123456789/1113
dc.description.abstract	A mild, efficient and versatile method has been developed for the construction of functionalized natural product (Meridianin) and its post conversion to pyrimido-β-carboline using cationic π- cyclization. The strategy involves the introduction of an amino group on the C-5 of the pyrimidine ring and utilising the nucleophilictiy of the C-2 in the indole ring to facilitate cationic π-cyclization.	en
dc.format.extent	1015921 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CSIR-CDRI Communication No. 8330	en
dc.subject	Indole	en
dc.subject	Natural products	en
dc.subject	Meridianin	en
dc.subject	Cyclization	en
dc.subject	Nitrogen Heterocycles	en
dc.title	Engineering of indole-based tethered biheterocyclic alkaloid Meridianin into -carboline derived tetracyclic polyheterocycles via amino functionalization/6-endo cationic π-cyclization.	en
dc.type	Article	en