Abstract:
A mild, efficient and versatile method has been developed for the construction of functionalized natural product (Meridianin) and its post conversion to pyrimido-β-carboline using cationic π- cyclization. The strategy involves the introduction of an amino group on the C-5 of the pyrimidine ring and utilising the nucleophilictiy of the C-2 in the indole ring to facilitate cationic π-cyclization.
