Abstract:
A simple and efficient procedure for the construction of 6, 6a-dihydroisoindolo[2,1-a]quinazoline 5,11-diones and 5-phenylisoindolo[2,1-a]quinazolin-11(6aH)-one derivatives in acetic acid under catalyst-free conditions is described. Attractive features of this methodology are its versality, the readily available starting materials needed and the efficiency in creating a complex core in a single operation.
