An efficient entry to highly substituted chiral 2-oxopiperazines from α-amino acids via iodocyclization

Jana, A K; Das, S K; Panda, Gautam

dc.contributor.author	Jana, A K
dc.contributor.author	Das, S K
dc.contributor.author	Panda, Gautam
dc.date.accessioned	2013-02-05T09:28:14Z
dc.date.available	2013-02-05T09:28:14Z
dc.date.issued	2012
dc.identifier.citation	Tetrahedron 2012, 68, (49), 10114–10121	en
dc.identifier.uri	http://hdl.handle.net/123456789/995
dc.description.abstract	A short and stereoselective route for the synthesis of 2-oxopiperazines is presented starting from different naturally abundant α-amino acids. The key synthetic steps involved amide coupling, Wittig reaction, HWE olefination, aza-Michael reaction, iodocyclization. This new pathway involving first report of iodocyclization to construct chiral substituted 2-oxopiperazines furnished final compounds in good yields.	en
dc.format.extent	415412 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI communication no. 8327	en
dc.subject	Oxopiperazines	en
dc.subject	Stereoselective	en
dc.subject	Iodocyclization	en
dc.title	An efficient entry to highly substituted chiral 2-oxopiperazines from α-amino acids via iodocyclization	en
dc.type	Article	en