A Chiron Approach to Aminocytitols by Petasis-Borono-Mannich Reaction: Formal Synthesis of (+)-Conduramine E and (-)-Conduramine E

Ghosal, Partha; Shaw, A K

dc.contributor.author	Ghosal, Partha
dc.contributor.author	Shaw, A K
dc.date.accessioned	2013-02-04T09:02:05Z
dc.date.available	2013-02-04T09:02:05Z
dc.date.issued	2012
dc.identifier.citation	Journal of Organic Chemistry 2012, 77 (17), 7627–7632	en
dc.identifier.uri	http://hdl.handle.net/123456789/991
dc.description.abstract	A chiron approach to stereoselective route for the synthesis of aminocytitols from carbohydrates is described. The formal synthesis of (+)-conduramine E and (-)-conduramine E was achieved by utilizing this strategy. The key features of the synthetic strategy include one pot three component Petasis-Borono-Mannich reaction to introduce the syn-ß-amino alcohol functionality of conduramine E and ring closing metathesis to construct its carbocyclic core. The present synthetic approach paves the way for stereoselective synthesis of several conduramines starting from carbohydrates	en
dc.format.extent	886642 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication no. 8302	en
dc.subject	Stereoselective	en
dc.subject	Carbohydrates	en
dc.subject	Aminocytitols	en
dc.title	A Chiron Approach to Aminocytitols by Petasis-Borono-Mannich Reaction: Formal Synthesis of (+)-Conduramine E and (-)-Conduramine E	en
dc.type	Article	en