Abstract:
Vibrio cholerae and related vibrios reduce aromatic nitro compounds, including chloramphenicol, producing the corresponding arylamines. An active cell-free preparation of this enzyme has been made and factors affecting
its activity have been studied. Chlorotetracycline, which has been shown to inhibit the E. coli enzyme, is without any action on the V. cholerae extract. Isonicotinic acid hydrazide, however, is found to be Inhibitory.