Abstract:
A series of sulphides. pyrimidines and quinazolones have been screened against experimental tuberculosis in guinea-pigs. Only p,p'-diaminodiphenyl sulphide (D.D. sulphide) has been found comparable to Dapsone (DDS). Isoniazid (INH) and dihydrostreptomycin sulphate (DHS). A high correlation between the spleen weight and pathologfcal scores has been established