Cascade intermolecular Michael addition-intramolecular azide/ internal alkyne 1,3-dipolar cycloaddition reaction in one-pot

Arigela, R K; Mandadapu, A K; Sharma, S K; Kumar, Brijesh; Kundu, Bijoy

dc.contributor.author	Arigela, R K
dc.contributor.author	Mandadapu, A K
dc.contributor.author	Sharma, S K
dc.contributor.author	Kumar, Brijesh
dc.contributor.author	Kundu, Bijoy
dc.date.accessioned	2012-09-17T10:41:08Z
dc.date.available	2012-09-17T10:41:08Z
dc.date.issued	2012
dc.identifier.citation	Organic Letters, 2012, 14 (7), 1804–1807	en
dc.identifier.uri	http://hdl.handle.net/123456789/918
dc.description.abstract	A rapid one-pot protocol for the synthesis of indole-based polyheterocycles via a sequential Lewis acid catalyzed intermolecular Michael addition and an intramolecular azide/internal alkyne 1,3-dipolar cycloaddition reaction has been described. The generality of the method has been demonstrated by treating a series of aromatic/aliphatic 2-alkynyl indoles with substituted (E)-1-azido-2-(2-nitrovinyl)benzenes to furnish annulated tetracyclic indolo[2,3-c][1,2,3]triazolo[1,5-a][1]benzazepines in good yields.	en
dc.format.extent	124693 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication No.8217	en
dc.subject	Polyheterocycles	en
dc.subject	2-alkynyl	en
dc.subject	Tetracyclic indolo	en
dc.subject	1,3-dipolar cycloaddition	en
dc.title	Cascade intermolecular Michael addition-intramolecular azide/ internal alkyne 1,3-dipolar cycloaddition reaction in one-pot	en
dc.type	Article	en