Studies in Potential Amoebicides:Part VI-Synthesis of Some I-(C-alkyl-3:4 -dimethoxyphenylalkylamino) -5-(3: 4-dimethoxyphenylalkylamino)-pentanes & i-Piperidyl-y-alkyl, Phenylalkyl & Furfuryl Aminopentanes

Abstract

The synthesis of 1-(N-ethyl-3:4-dimethoxybenzylamino)-5 -(3, 4 -dimethoxyphenylethylino,3, 4-dlmethoxybenzylamino, isopropylamino and furfurylamino)-pentanes, and 1-(N-methyl-3: 4-dimethoxyphenylethylamino)-5-(3,4 -dimethoxybenzylamino) -pentane as simple analogues of emetine is reported. The synthesis of some I-piperidino-5-substituted aminopentanes is also reported.