Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic ﬁlarial parasite, Brugia malayi

Sashidhara, K V; Singh, S P; Misra, Sweta; Gupta, Jyoti; Bhattacharya-Misra, Shailja

dc.contributor.author	Sashidhara, K V
dc.contributor.author	Singh, S P
dc.contributor.author	Misra, Sweta
dc.contributor.author	Gupta, Jyoti
dc.contributor.author	Bhattacharya-Misra, Shailja
dc.date.accessioned	2012-06-27T10:06:55Z
dc.date.available	2012-06-27T10:06:55Z
dc.date.issued	2012
dc.identifier.citation	Eur J Med Chem. 2012, 50, 230-235	en
dc.identifier.uri	http://hdl.handle.net/123456789/783
dc.description.abstract	Bioassay guided fraction of ethanolic extract of the leaves of B. racemosa led to the isolation of galactolipid and catechin class of the compounds (1-7) from the most active n-butanol fraction (F4). Among the active galactolipids, 1 emerged as the lead molecule which was active on both forms of lymphatic filarial parasite, B. malayi. It was found to be better than the standard drug ivermectin and diethyl carbamazine (DEC) in terms of dose and efficacy.	en
dc.format.extent	395931 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication No. 8190	en
dc.subject	Bauhinia racemosa	en
dc.subject	galactolipids	en
dc.subject	antifilarial	en
dc.subject	Brugia malayi	en
dc.subject	jird	en
dc.title	Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic ﬁlarial parasite, Brugia malayi	en
dc.type	Article	en