Application of Huisgen (3+2) cycloaddition reaction: Synthesis of 1-(2,3-dihydrobnzofuran-2-yl methyl [1,2,3]-triazoles and their Antitubercular evaluations

Tripathi, R P; Yadav, A K; Bisht, S S; Chaturvedi, Vinita; Sinha, S K

dc.contributor.author	Tripathi, R P
dc.contributor.author	Yadav, A K
dc.contributor.author	Bisht, S S
dc.contributor.author	Chaturvedi, Vinita
dc.contributor.author	Sinha, S K
dc.date.accessioned	2012-05-24T04:51:38Z
dc.date.available	2012-05-24T04:51:38Z
dc.date.issued	2010
dc.identifier.citation	European journal of medicinal chemistry, 2010, 45(1), 142–148	en
dc.identifier.uri	http://hdl.handle.net/123456789/768
dc.description.abstract	1, 4-disubstituted -1, 2, 3-triazoles (3-27) have been synthesized by [3+2] cycloaddition of different 2-(azidomethyl)- dihydronaptho (benzo)furans (2a, 2b, 2c and 2d) with different alkynes. All the compounds were screened for antitubercular activity against Mycobacetrium tuberculosis H37Rv. Compounds 2a, 7, 9, 12 and 14 exhibited antitubercular activities with MIC ranging from 12.5 to 3.12 g/ml	en
dc.format.extent	864419 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication No.7771	en
dc.subject	Triazoles	en
dc.subject	Huisgen [3 + 2] cycloaddition	en
dc.subject	copper catalyst	en
dc.subject	antitubercular agents	en
dc.title	Application of Huisgen (3+2) cycloaddition reaction: Synthesis of 1-(2,3-dihydrobnzofuran-2-yl methyl [1,2,3]-triazoles and their Antitubercular evaluations	en
dc.type	Article	en