ANTIDYSLIPIDEMIC AND ANTIOXIDANT ACTIVITY OF PINUS ROXBERGHII NEEDLES

Puri, Anju; Srivastava, A K; Singhal, Barkha; Mishra, S K; Srivastava, S; Lakshmi, Vijay

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dc.contributor.author	Puri, Anju
dc.contributor.author	Srivastava, A K
dc.contributor.author	Singhal, Barkha
dc.contributor.author	Mishra, S K
dc.contributor.author	Srivastava, S
dc.contributor.author	Lakshmi, Vijay
dc.date.accessioned	2012-04-18T11:33:53Z
dc.date.available	2012-04-18T11:33:53Z
dc.date.issued	2009
dc.identifier.citation	Medicinal Chemistry Research 2011,20(9), 1589-1593	en
dc.identifier.uri	http://hdl.handle.net/123456789/757
dc.description.abstract	Pinus roxburghii commonly known as Chir pine contains a substance turpene in abundance and is known for several medicinal properties. The needles were investigated for antidyslipidemic activity in high fat diet (HFD) fed hyperlipidemic Golden-Syrian hamsters. The alcoholic extracts of P. roxburghii needle showed a significant decrease in lipid profile at the dose of 100 mg/kg. Further extraction with different solvents showed increased lipid lowering profile in hexane soluble and N-butenol soluble fractions. Antioxidant activity of all the fractions was assessed and found to be significant in alcoholic extract and N-butenol insoluble fractions as capacity to scavenge the ABTS + radical cation. In vitro	en
dc.format.extent	620981 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication No. 7794	en
dc.subject	Antidyslipidemic activity	en
dc.subject	antioxidant activity	en
dc.subject	Pinus roxburghii	en
dc.subject	antioxidative agents	en
dc.subject	hamster model	en
dc.title	ANTIDYSLIPIDEMIC AND ANTIOXIDANT ACTIVITY OF PINUS ROXBERGHII NEEDLES	en
dc.type	Article	en