Synthetic studies towards potent cytostatic macrolide rhizopodin: stereoselective synthesis of the C16-C28 fragment†

Chakraborty, T K; Sreekanth, Midde; Pulukuri, K K

dc.contributor.author	Chakraborty, T K
dc.contributor.author	Sreekanth, Midde
dc.contributor.author	Pulukuri, K K
dc.date.accessioned	2011-05-23T04:17:02Z
dc.date.available	2011-05-23T04:17:02Z
dc.date.issued	2011
dc.identifier.citation	Tetrahedron Letters,52(1),59-61	en
dc.identifier.uri	http://hdl.handle.net/123456789/675
dc.description.abstract	A stereoselective synthesis of the C16-C28 fragment of cytostatic C2-symmetric macrolide rhizopodin is described. Enantioselective addition of a chiral thiazolidinethione derived titanium enolate to acetal, Evans' aldol reaction, Horner–Wadsworth–Emmons reaction and Mukaiyama aldol reaction were applied as key steps.	en
dc.format.extent	1276377 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	cdricommunicationno.7980	en
dc.subject	Rhizopodin	en
dc.subject	cytostatic	en
dc.subject	actin polymerization	en
dc.subject	inhibitor	en
dc.subject	diolides	en
dc.subject	aldol reaction	en
dc.title	Synthetic studies towards potent cytostatic macrolide rhizopodin: stereoselective synthesis of the C16-C28 fragment†	en
dc.type	Article	en