Cassane Diterpenes from Caesalpinia bonduc

Yadava, P P; Maurya, Ranjani; Sarkar, Jayanta; Arora, Ashish; Kanojiya, Sanjeev; Sinha, Sudhir; Srivastava, M N; Raghubir, Ram

dc.contributor.author	Yadava, P P
dc.contributor.author	Maurya, Ranjani
dc.contributor.author	Sarkar, Jayanta
dc.contributor.author	Arora, Ashish
dc.contributor.author	Kanojiya, Sanjeev
dc.contributor.author	Sinha, Sudhir
dc.contributor.author	Srivastava, M N
dc.contributor.author	Raghubir, Ram
dc.date.accessioned	2010-09-09T08:57:03Z
dc.date.available	2010-09-09T08:57:03Z
dc.date.issued	2009
dc.identifier.citation	Phytochemistry,70(2)2009-256-261	en
dc.identifier.uri	http://hdl.handle.net/123456789/604
dc.description.abstract	Three new cassane diterpene hemiketals, caesalpinolide-C (1), caesalpinolide-D (2), caesalpinolide-E (3) and one new cassane furanoditerpene (4) were isolated from Caesalpinia bonduc. Molecular structure of new compounds were elucidated using NMR spectroscopy in combination with IR, UV and mass spectral data and relative stereochemistries were determined through ROESY correlation. The isolated compounds were tested for their antiproliferative activity in MCF-7 (breast adenocarcinoma), DU145 (prostate carcinoma), C33A (Cervical carcinoma) and Vero (African green monkey kidney fibroblast) cells.	en
dc.format.extent	236000 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.subject	Caesalpinia bonduc	en
dc.subject	Fabaceae	en
dc.subject	phytochemistry	en
dc.subject	cassane diterpenes	en
dc.subject	butenolides	en
dc.subject	furanoditerpenes	en
dc.subject	antiproliferative activity	en
dc.title	Cassane Diterpenes from Caesalpinia bonduc	en
dc.type	Article	en