Application of phenolate ion-mediated intramolecular epoxide ring opening in the enantioselective synthesis of functionalized 2,3-dihydrobenzofuran and 1-benzopyran derivatives

Dinda, S K; Das, S K; Panda, Gautam

dc.contributor.author	Dinda, S K
dc.contributor.author	Das, S K
dc.contributor.author	Panda, Gautam
dc.date.accessioned	2010-09-09T08:52:45Z
dc.date.available	2010-09-09T08:52:45Z
dc.date.issued	2009
dc.identifier.citation	Synthesis, 2009, 11, 1886-1896	en
dc.identifier.uri	http://hdl.handle.net/123456789/590
dc.description.abstract	The enantioselective synthesis of 2-isopropenyl-2,3-dihydrobenzofurans, 4-(2,3-dihydrobenzofuran-2-yl)-2-methylbut-3-en-2-ols, 2-hydroxymethylchromans, and 4-chroman-2-yl-2-methyl-but-3-en-2-ols has been achieved using Sharpless asymmetric epoxidation-derived enantiomerically enriched epoxy alcohols as chiral building blocks. A phenolate ion-mediated intramolecular epoxide ring opening reaction was the key step for every cyclization reaction.	en
dc.format.extent	247815 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.subject	2-isopropenyl-2,3-dihydrobenzofuran	en
dc.subject	2-hydroxymethyl chromans	en
dc.subject	Epoxidation	en
dc.subject	Epoxides	en
dc.subject	Polycycles	en
dc.subject	Ring opening	en
dc.title	Application of phenolate ion-mediated intramolecular epoxide ring opening in the enantioselective synthesis of functionalized 2,3-dihydrobenzofuran and 1-benzopyran derivatives	en
dc.type	Article	en