Parasitology: Recent submissions

Now showing items 41-47 of 47

Antileishmanial activity of benzocycloalkyl azole oximino ethers: The conformationally constraint analogues of oxiconazole

Verma, Aditya; Srivastava, Saumya; Sane, S A; Marrapu, V K; Srinivas, Nagarapu; Yadav, Manisha; Bhandari, Kalpana; Gupta, Suman (2011)

Antileishmanial activities of 16 synthetic oximino benzocycloalkyl azoles against Leishmania donovani were evaluated in vitro against extracellular promastigotes and intracellular amastigotes. Based on SI (Selectivity ...
Photodynamic vaccination of hamsters with inducible suicidal mutants of Leishmania amazonensis elicits immunity against visceral leishmaniasis

Kumari, Shraddha; Samant, Mukesh; Khare, Prashant; Misra, Pragya; Dutta, Sujoy; Kolli, B K; Sharma, Sharad; Chang, K P; Dube, Anuradha (2009)

Leishmania, naturally residing in the phagolysosomes of macrophages, is a suitable carrier for vaccine delivery. Genetic complementation of these trypanosomatid protozoa to partially rectify their defective heme-biosynthesis ...
Reporter genes facilitating discovery of drugs targeting protozoan parasites

Dube, Anuradha; Gupta, Reema; Singh, Nasib (2009)

Transfection of protozoan parasites, such as Plasmodium, Leishmania, Trypanosoma and Toxoplasma, with various reporter gene constructs, has revolutionized studies to understand the biology of the host–parasite interactions ...
Transgenic Leishmania donovani clinical isolates expressing GFP- constitutively for rapid and reliable ex-vivo drug screening

Nasib Singh, Reema Gupta; Jaiswal, A K; Sundar, Shyam; Dube, Anuradha (2009)

Objectives: Several Leishmania strains with episomal expression of green fluorescent protein (GFP) require constant drug pressure for its continuous expression and hence limit its use for ex-vivo or in-vivo system. The aim ...
Reporter genes facilitating discovery of drugs targeting protozoan parasites

Dube, Anuradha; Gupta, Reema; Singh, Nasib (2009)

Transfection of protozoan parasites, such as Plasmodium, Leishmania, Trypanosoma and Toxoplasma, with various reporter gene constructs, has revolutionized studies to understand the biology of the host–parasite interactions ...
A pro-apoptotic effect of Landrace of Piper betle- Bangla Mahoma on Leishmania donovani may be due to high content of eugenol

Misra, Pragya; Kumar, Awanish; Gupta, Swati; Khare, Prashant; Kumar, Nikhil; Dube, Anuradha (2009)

In the absence of effective and safe treatment of Kala-azar (VL) - a most devastating parasitic disease caused by Leishmania donovani a need for the search of antileishmanial from natural resources, in common use, is ...
Identification of genetic markers in Sodium Antimony Gluconate (SAG) sensitive and resistant Indian clinical isolates of Leishmania donovani through Amplified Fragment Length Polymorphism (AFLP)

Kumar, Awanish; Boggula, V R; Sundar, Shyam; Shasany, A K; Dube, Anuradha (2009)

Sodium Antimony Gluconate (SAG) is currently used worldwide as the first-line drugs for the treatment of visceral leishmaniasis (VL) and cutaneous leishmaniasis (CL) since 1940s. Unfortunately, the resistance of Leishmania ...

Now showing items 41-47 of 47

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