Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives

Nag, Somnath; Pathak, Richa; Kumar, Manish; Shukla, P K; Batra, Sanjay

dc.contributor.author	Nag, Somnath
dc.contributor.author	Pathak, Richa
dc.contributor.author	Kumar, Manish
dc.contributor.author	Shukla, P K
dc.contributor.author	Batra, Sanjay
dc.date.accessioned	2007-12-26T10:26:00Z
dc.date.available	2007-12-26T10:26:00Z
dc.date.issued	2006
dc.identifier.citation	Bioorganic & Medicinal Chemistry Letters, 16, 3824 (2006)	en
dc.identifier.uri	http://hdl.handle.net/123456789/51
dc.description.abstract	The synthesis of several 1-(2-cyano-3-aryl-allyl)-3-aryl-urea(thiourea) constructed from the reaction between allyl amines generated from Baylis-Hillman acetates and substituted isocyanates and isothiocyanates has been described. Further their cyclization in the presence of a base led to the formation of 5-arylmethyl-4-imino-3-aryl-3,4-dihydro-1H-pyrimidin-2-ones. All compounds were tested for their antibacterial activity. Few of the compounds showed superior activity or were equipotent to the standard antibacterial agents.	en
dc.format.extent	148835 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication no. 6933	en
dc.subject	Ureides	en
dc.subject	Baylis-Hillman	en
dc.subject	antibacterial	en
dc.title	Synthesis and antibacterial evaluation of ureides of Baylis-Hillman derivatives	en
dc.type	Article	en