Abstract:
Global efforts had been continued for the last 50) years, to find a safe radical curative (anti-relapse) drug to replace primaquine for the treatment of Plasomodium vivax and P. ovale, Throughout the world, more than 250 potential tissue. schizontocides had been synthesized and screened, and two new primaquine derivatives had been identified in primate malaria radical curative tests which could be the candidate drugs to replace primaquine:
