Synthesis of substituted 1H- and 3H-1-benzazepines: Rearrangement of 2-alkoxycarbonyl-1H-1-benzazepines to isoquinolines

Singh, Vijay; Batra, Sanjay

dc.contributor.author	Singh, Vijay
dc.contributor.author	Batra, Sanjay
dc.date.accessioned	2007-12-07T07:10:23Z
dc.date.available	2007-12-07T07:10:23Z
dc.date.issued	2007
dc.identifier.citation	Eur. J. Org. Chem., 2970-2979 ( 2007)	en
dc.identifier.uri	http://hdl.handle.net/123456789/39
dc.description.abstract	The SnCl2-mediated reduction of nitro groups in 2-nitro-4-(2-nitro-benzylidene)-alkanoates and 4-nitro-2-(2-nitro-alkylidene)-alkanoates afforded via SN2′ reaction of ethyl nitroacetate and nitroethane with the acetyl derivatives of Baylis-Hillman adducts afforded by 2-nitro-substituted benzaldehydes leads to facile synthesis of substituted 1H-1-benzazepine and 3H-1-benzazepine. During the study an unprecedented rearrangement of 2-alkoxycarbonyl-1H-benzazepine to substituted isoquinoline has been observed.	en
dc.format.extent	184488 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication no. 7149	en
dc.subject	Baylis-Hillman reaction	en
dc.subject	SnCl2.2H2O	en
dc.subject	Nitrogen heterocycles	en
dc.subject	Rearrangement.	en
dc.title	Synthesis of substituted 1H- and 3H-1-benzazepines: Rearrangement of 2-alkoxycarbonyl-1H-1-benzazepines to isoquinolines	en
dc.type	Article	en