New cassane butenolide hemiketal diterpenes from the marine creeper Caesalpinia honduc and their
antiproliferative activity

Yadav, P P; Arora, Ashish; Bid, H K; Konwar, Rituraj; Kanojiya, Sanjeev

dc.contributor.author	Yadav, P P
dc.contributor.author	Arora, Ashish
dc.contributor.author	Bid, H K
dc.contributor.author	Konwar, Rituraj
dc.contributor.author	Kanojiya, Sanjeev
dc.date.accessioned	2007-11-14T09:43:17Z
dc.date.available	2007-11-14T09:43:17Z
dc.date.issued	2007
dc.identifier.citation	Tetrahedron Letters 48 (2007) 7194-7198	en
dc.identifier.uri	http://hdl.handle.net/123456789/19
dc.description.abstract	Two new cassane butenolides, caesalpinolide A (1) and B (2), epimeric at the hemiketal position were isolated from the marine creeper Caesalpinia bonduc. The structures were elucidated by the analysis of spectroscopic data and relative stereochemistry was assigned on the basis of ROESY correlations. Compounds 1 and 2 were found to inhibit MCF-7 breast cancer cell lines with ICso values of (IlM)12.8 and 6.1, respectively, along with the inhibition of endometrial and cervical cancer cell lines	en
dc.format.extent	582825 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication Number 7219	en
dc.title	New cassane butenolide hemiketal diterpenes from the marine creeper Caesalpinia honduc and their antiproliferative activity	en
dc.type	Article	en