Formal acylamination of nitroalkenes in aqueous medium for the synthesis of 2-aryl-3-nitro-2,3-dihydro-quinolin-4(1H)-ones

Abstract

Formal acylamination of aromatic nitroalkenes with 2-aminobenzoyl benzotriazoles in aqueous methanol results into diastereoselective synthesis of 2-aryl-3-nitro-2,3-dihydro-quinolin-4(1H)-ones. The aliphatic nitroalkenes however form Michael addition product with benzotriazole