Synthesis and Biotinylation of Oligosaccharide Fragments of Mannosylated and 5-Deoxy-5-methylthio-xylofuranosylated Lipoarabinomannan from Mycobacterium tuberculosis

Mandal, P K; Chheda, P R

dc.contributor.author	Mandal, P K
dc.contributor.author	Chheda, P R
dc.date.accessioned	2015-03-20T11:31:56Z
dc.date.available	2015-03-20T11:31:56Z
dc.date.issued	2015
dc.identifier.citation	Carbohydrate Research, 2015, 407, 104-110.	en
dc.identifier.uri	http://hdl.handle.net/123456789/1434
dc.description.abstract	The attachment of biotin to a molecule provides a powerful tool in biology. Here, we report an efficient synthesis and biotinylation of mannosylated and 5-deoxy-5-methylthio-xylofuranosylated Lipoarabinomannan from Mycobacterium tuberculosis. Preparation of the oligosaccharides involved the sequential addition of thioglycoside donors with arabinofuranosyl-containing acceptors. Methylthio group was introduced near the end of the synthesis.	en
dc.format.extent	293709 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CSIR-CDRI Communication No. 8889	en
dc.subject	Tuberculosis(TB)	en
dc.subject	5-deoxy-5-methylthio-xylofuranose (MTX)	en
dc.subject	Glycosylation	en
dc.subject	Biotin	en
dc.subject	Lipoarabinomannan (LAM)	en
dc.title	Synthesis and Biotinylation of Oligosaccharide Fragments of Mannosylated and 5-Deoxy-5-methylthio-xylofuranosylated Lipoarabinomannan from Mycobacterium tuberculosis	en
dc.type	Article	en