Abstract:
Allylamine is one of the most fundamental units in organic chemistry which has been engineered to afford a diverse range of complex structural frameworks. This review encompasses the literature from 2006 to May 2010 concerning the utility of allylamine or substituted allylamines for the synthesis of aza-heterocycles. Reactions covered in this report include nucleophilic reactions, lactamizations, cycloadditions, free radical reactions, cross-couplings and reductive cyclizations. To limit the scope, however, ring-closing metatheses, Pauson-Khand reactions and cycloisomerizations are not included.