Ugi Four-Component Reaction with Tandem Deprotection, Cyclization and Pictet–Spengler Reaction: A Concise Route to N-Fused Polycyclic Indoledi­ketopiperazine Alkaloid Analogues

Tyagi, Vikas; Khan, Shahnawaz; Chauhan, P M S

dc.contributor.author	Tyagi, Vikas
dc.contributor.author	Khan, Shahnawaz
dc.contributor.author	Chauhan, P M S
dc.date.accessioned	2014-09-11T11:33:21Z
dc.date.available	2014-09-11T11:33:21Z
dc.date.issued	2013
dc.identifier.citation	Synlett, 2013, 24 (10), 1291-1297	en
dc.identifier.uri	http://hdl.handle.net/123456789/1402
dc.description.abstract	Aza-fused polycyclic indolediketopiperazine alkaloids are of potential interest due to their broad range of biological activities. Traditionally, a number of methods have been reported to generate N-fused polycyclic indolediketopiperazine skeletons, but the development of novel, concise methods to modify its substitution pattern are strongly required. Herein, we have described the two-step formation of N-fused polycyclic indolediketopiperazine alkaloid analogues by the application of the Ugi 4-CR with tandem deprotection-cyclization/Pictet-Spengler reaction	en
dc.format.extent	154987 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CSIR-CDRI Communication No. 8434	en
dc.subject	Indolediketopiperazine alkaloids	en
dc.subject	Ugi-multicomponent reaction	en
dc.subject	Tandem reaction	en
dc.subject	Deprotection-cyclization reactions	en
dc.subject	Pictet-Spengler reaction	en
dc.title	Ugi Four-Component Reaction with Tandem Deprotection, Cyclization and Pictet–Spengler Reaction: A Concise Route to N-Fused Polycyclic Indolediketopiperazine Alkaloid Analogues	en
dc.type	Article	en