Synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines via cascade imination/intramolecular decarboxylative coupling

Pandey, Garima; Bhowmik, Subhendu; Batra, Sanjay

dc.contributor.author	Pandey, Garima
dc.contributor.author	Bhowmik, Subhendu
dc.contributor.author	Batra, Sanjay
dc.date.accessioned	2014-06-20T07:45:33Z
dc.date.available	2014-06-20T07:45:33Z
dc.date.issued	2013
dc.identifier.citation	Organic Letters, 2013, 15(19), 5044-7	en
dc.identifier.uri	http://hdl.handle.net/123456789/1288
dc.description.abstract	A general approach for the synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines is described involving the implementation of a cascade imination/ intramolecular decarboxylative coupling between potassium 2-amino(hetero)benzoates and 2-haloarylaldehydes. The reactions of pyrazole-based substrates require a Pd-Cu bimetallic system for superior yields whereas the thienyl-based substrates afford the products in excellent yields with Pd-catalyst only.	en
dc.format.extent	268746 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CSIR-CDRI communication No. 8542	en
dc.subject	Synthesis	en
dc.subject	3H-pyrazolo[3,4-c]isoquinolines	en
dc.subject	thieno[3,2-c]isoquinolines	en
dc.subject	cascade	en
dc.subject	decarboxylative coupling	en
dc.title	Synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines via cascade imination/intramolecular decarboxylative coupling	en
dc.type	Article	en