Microwave assisted three component domino reaction: Synthesis of Indolodiazepinotriazoles

Arigela, R K; Sharma, S K; Kumar, Brijesh; Kundu, Bijoy

dc.contributor.author	Arigela, R K
dc.contributor.author	Sharma, S K
dc.contributor.author	Kumar, Brijesh
dc.contributor.author	Kundu, Bijoy
dc.date.accessioned	2013-04-15T05:35:49Z
dc.date.available	2013-04-15T05:35:49Z
dc.date.issued	2013
dc.identifier.citation	Beilstein Journal of Organic Chemistry 2013, 9, 401–405	en
dc.identifier.uri	http://hdl.handle.net/123456789/1044
dc.description.abstract	A microwave assisted three component protocol involving N-1 alkylation of 2-alkynylindoles with epichlorohydrin, ring opening of the epoxide with sodium azide and intramolecular Huisgen azide/internal alkyne 1,3-dipolar cycloaddition domino sequence has been described. The efficacy of the methodology has been demonstrated by treating various 2-alkyl indoles (aromatic/aliphatic) with epichlorohydrin and sodium azide furnishing annulated tetracyclic indolodiazepinotriazoles in satisfactory yields	en
dc.format.extent	653473 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication No. 8380	en
dc.subject	1, 3-dipolar cycloaddition	en
dc.subject	domino reaction	en
dc.subject	Azides; 2-alkynyl indoles	en
dc.subject	indolodiazepinotriazoles	en
dc.title	Microwave assisted three component domino reaction: Synthesis of Indolodiazepinotriazoles	en
dc.type	Article	en