Expeditious synthesis of chiral 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazines

Bhowmik, Subhendu; Kumar, A K S; Batra, Sanjay

dc.contributor.author	Bhowmik, Subhendu
dc.contributor.author	Kumar, A K S
dc.contributor.author	Batra, Sanjay
dc.date.accessioned	2013-04-05T10:29:35Z
dc.date.available	2013-04-05T10:29:35Z
dc.date.issued	2013
dc.identifier.citation	Tetrahedron Letters 2013, 54(18), 2251–2254	en
dc.identifier.uri	http://hdl.handle.net/123456789/1042
dc.description.abstract	An expeditious one-pot two-step synthesis of chiral 4-substituted-6-methyl-1,2-dihydropyrrolo[1,2-a]pyrazin-3(4H)-ones via reaction between 5-methyl furfurylamine and N-Boc amino acids is described. LiAlH4-mediated reduction of 4-substituted-6-methyl-1,2-dihydropyrrolo[1,2-a]pyrazin-3(4H)-ones afford respective chiral 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazines in excellent yields.	en
dc.format.extent	225469 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication No. 8413	en
dc.subject	1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazines	en
dc.subject	Amino acid	en
dc.subject	Furfurylamine	en
dc.subject	Reduction	en
dc.subject	chiral	en
dc.title	Expeditious synthesis of chiral 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazines	en
dc.type	Article	en