Antidyslipidemic and antioxidant activity of the constituents isolated from the leaves of Calophyllum inophyllum

Prasad, Janki; Shrivastava, Atul; Khanna, A K; Bhatia, G; Awasthi, S K; Narender, T

dc.contributor.author	Prasad, Janki
dc.contributor.author	Shrivastava, Atul
dc.contributor.author	Khanna, A K
dc.contributor.author	Bhatia, G
dc.contributor.author	Awasthi, S K
dc.contributor.author	Narender, T
dc.date.accessioned	2013-03-06T06:19:51Z
dc.date.available	2013-03-06T06:19:51Z
dc.date.issued	2012
dc.identifier.citation	Phytomedicine 2012, 19 (14), 1245–1249	en
dc.identifier.uri	http://hdl.handle.net/123456789/1006
dc.description.abstract	In continuation of our drug discovery program on Indian medicinal plants, we isolated bioactive compounds (1-5) from the leaves of Calophyllum inophyllum and evaluated their antidyslipidemic activity in triton induced hyperlipidemia model. The calophyllic acid (1A) and isocalophyllic acid (1B) mixture, canophyllic acid (4) and amentoflavone (5) showed dose dependent lipid lowering activity in in-vivo experiments. The compounds 1A + 1B mixture and 3 also showed good in-vitro antioxidant activity.	en
dc.format.extent	177081 bytes
dc.format.mimetype	application/pdf
dc.language.iso	en	en
dc.relation.ispartofseries	CDRI Communication No. 8322	en
dc.subject	Calophyllum inophyllum	en
dc.subject	Antidyslipidemic activity	en
dc.subject	Triton model	en
dc.subject	Antioxidant activity	en
dc.title	Antidyslipidemic and antioxidant activity of the constituents isolated from the leaves of Calophyllum inophyllum	en
dc.type	Article	en